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1.
Indian J Pathol Microbiol ; 2022 Jun; 65(2): 452-454
Article | IMSEAR | ID: sea-223255

ABSTRACT

Aneurysmal bone cyst (ABC) is a benign expansile cystic lesion that can affect any bone of the skeleton, especially the femur, tibia, and humerus. Lesions with histologic features of an ABC can be originated within soft tissue in exceedingly rare cases. Extra-skeletal ABC may mimic a variety of benign and malignant lesions and can be confused with other common or rare giant cell-rich tumors of soft tissue. Clinical, radiological and histologic correlation are crucial in reaching the correct diagnosis. Here we report a case of an extra-skeletal ABC arising in left hemithorax in a 13-year-old girl and discuss the common differential diagnosis of this rare entity.

2.
Article | IMSEAR | ID: sea-205617

ABSTRACT

Background: The energy requirement of an individual can be defined as the level of energy intake from food that will balance the energy expenditure. Dietary intakes lower or higher than the body requirements can lead to undernutrition (deficiency diseases) or overnutrition (diseases of affluence), respectively. Per day calorie intake influences various daily energy utilizing activities. The imbalance between intake and expenditure continues over long periods, changes in body weight or body composition will occur and may adversely affect health. The resting energy expenditure (REE), the largest portion (50–75%) of total energy expenditure, is the energy required to maintain the basic metabolic activities including maintaining the body temperature and keeping the functioning of vital organs such as brain, kidneys, heart, and lungs. Hence, REE plays the most important role in body functioning. Objective: The aim and objective of the present study were to access the effect of per day calorie intake on REE. Materials and Methods: One hundred subjects (age 18–25 years) were assessed for data collection. All the data were collected in the early morning hours. The study was approved by the Institutional Ethical Committee (EC/P-47/2018) of Rajasthan University of Health Sciences College of Medical Sciences, Jaipur. Demographic data including the anthropometric measurement of the participants such as weight, height, and body mass index (BMI). Calories intake (kcal) in 24 h was measured using food frequency questionnaire. Moreover, REE was measured using the gold standard method indirect calorimetry. Pearson correlation was calculated to seen correlation between per day calorie intake and REE. Results: A total of 75 males and 25 females with mean age of males and females were 19.97 ± 1.81 years and 19.32 ± 1.75 years, respectively. The mean BMI was 21.77 ± 4 kg/m² of males and 22.68 kg/m² of females. The mean calorie intake was 2532.082 ± 830.970 kcal in males and 1991.176 ± 783.291 kcal in females. The mean REE of male subjects was 2081.470 ± 587.661 kcal and of females was 1827.895 ± 469.671 kcal. The present study results showed the positive poor correlation (r = +0.1572) between calorie intake and REE in male subjects and negative poor correlation (r = −0.1484) in female subjects. Conclusion: The present study results concluded that there was a poor association between per day calorie intake and REE. Moreover, on the basis of the present study results, we can also say that most of our energy intake was expended to maintain body functioning at rest.

3.
Article | IMSEAR | ID: sea-196468

ABSTRACT

Introduction: Uterine tumors resembling ovarian sex cord tumor (UTROSCT) are a unique group of neoplasms with diverse morphology and immunophenotypic characteristics, coexpressing sex cord, epithelial, and smooth-muscle markers. To date, less than 100 cases have been reported and there is paucity of data concerning their clinical behavior. Materials and Methods: All cases of uterine body tumors diagnosed over a period of two and a half years (2016-2018) were retrieved. Histopathological features were reviewed and extended panel of immunohistochemistry was performed to identify cases of UTROSCTs. Results: Six cases of UTROSCTs were identified with a median age of 46.5 years. Four of them presented with menorrhagia, while two with postmenopausal bleeding including one with a history of carcinoma breast. Three of these cases were initially misdiagnosed as endometrial stromal sarcoma and adenocarcinomas. They all underwent hysterectomy with bilateral salpingo-oophorectomy. Conclusion: It is considered a tumor with low malignant potential; however, one out of six cases (16.7%) in our study showed metastasis, within 1 year of diagnosis. It is important to recognize this entity as it mimics a wide range of both benign and malignant tumors. Molecular pathogenesis and exact management protocols remain elusive due to rarity,hence, multi-institutional studies are warranted.

4.
Article | IMSEAR | ID: sea-198719

ABSTRACT

Variations of nerve are not only of anatomic and embryological interest but also of clinical importance. Theiradequate knowledge certainly help in increasing surgical precision and decreasing morbidity. In present studyvariations in mode of origin and level of formation of nerve to medial and lateral head of gastrocnemius wasstudied. The material for the present study comprised of 60 lower extremities belonging to 30 adult humancadavers obtained from Department of Anatomy, PIMS, Jalandhar. Neurectomy of nerve to medial gastrocnemiusmuscle is used to reduce volume of the muscle. For facial reconstruction after total parotidectomy, the facialnerve is being reconstructed by using vascularized sural nerve with free lateral gastrocnemius muscle flap

5.
Article | IMSEAR | ID: sea-205566

ABSTRACT

Background: Adolescents (10–19 years) constitute about one-fifth (21.4%) of India’s population. It has been identified as one of the vulnerable periods of life when the various health problems may occur. The prevalence of mental health problems among adolescents in India varies from 8.7% to 31.2% as shown in different studies. Objectives: The objectives of this study were to estimate the prevalence of mental health issues, violence, bullying, and unintentional injuries among adolescents. Materials and Methods: The present study is an observational descriptive study. After obtaining ethical clearance from the institutional ethics committee, 100 students from rural and 100 from urban areas of both sexes were randomly selected. A questionnaire based on global school-based student health survey was prepared. Responses obtained from self-administered questionnaire were entered into Microsoft Excel. Data were analyzed in Microsoft Excel using simple proportions and Chi-square test to find statistical significance if any. Results: About 11% felt lonely most of times, 13.5% had difficulty in sleeping at most of nights, and 2.5% even considered of attempting suicide. Girls (15%) reported being bullied more as compared to boys who reported it to be 9%. Furthermore, reports were more for urban area (15%) than for rural one (9%). Conclusion: Adolescents are being bullied or get involved in a physical fight (17%). Mental health issues are also widely prevalent among them. About 28% felt lonely, 30.5% could not sleep at night, and 2.5% even considered attempting suicide.

6.
J Environ Biol ; 2019 Sep; 40(5): 1102-1108
Article | IMSEAR | ID: sea-214633

ABSTRACT

Aim: Development of commercial hybrid of sunflower on basis of best inbred combination remains a key challenge to sunflower breeders. In the current investigation, heterosis of F1 hybrids, parental genetic diversity and correlation between genetic distance and level of heterosis were estimated. Methodology: Thirty five parental genotypes (3 CMS A lines and 32 R lines) and their hybrids were assessed for physio-morphological, yield and quality traits. Heterosis was measured as mid-parent and better parent heterosis. Among parents, SSR marker based genetic distances were calculated using DARwin software. Correlation between heterosis and genetic distances was carried out by Karl Pearson’s simple correlation method. Results: Range of genetic distances, based on SSR marker analysis, varied from 0.32-0.73. Genetic distance had significant positive correlation with the heterosis for oil content (r = 0.22 p<0.05) and linoleic acid (r = 0.32 p<0.05), but negative correlation was observed for days to maturity, test weight, volume weight, stearic acid and oleic acid. There was no significant correlation between genetic distance and heterosis for seed yield and other agronomic traits. Interpretation: Although, genetic distance is poor predictor of heterosis, dependence of oil content on genetic distance among parental lines may be used for designing an effective breeding program for sunflower.

7.
Article | IMSEAR | ID: sea-198605

ABSTRACT

Background: The Medical Council of India has visualized the effective outcome based strategy of CompetencyBased Medical Education where the assessment is the essential component of competencies. Formative assessmentis a systematic approach designed for students during a particular period of study to provide motivation forlearning. It helps the student to set the desired but attainable goals and to follow the steps required to achievethose specified goals.Aim: To introduce the feedback to the students during substages and after the theory tests and to assess studentsand teacher’s perspective towards feedback.Material and Method: The project was done in the Department of Anatomy, Punjab Institute of Medical Sciences,Jalandhar involving 1st year batch students and faculty members of Anatomy.Results: A good percentage of students were satisfied with the formative assessment and wanted the process tobe continued in the subsequent years too. All the faculty members had positive response for formative assessment.Conclusion: Formative assessment is the strategy to encourage the students for self directed learning and selfassessment.

8.
Article | IMSEAR | ID: sea-183587

ABSTRACT

Background: The axis vertebra, exhibits complex and extensive variability in the morphology and there are vital neurovascular structures in its proximity. Knowledge of this variability is important for neurosurgeons, orthopaedicians, otorhynologists and other physicians who in everyday practice are in contact with disorders of the spine and their consequences. Objective: The aim was to evaluate various morphometric dimensions of axis vertebrae and to compare with the available data. Material and Methods: 50 dried human axis vertebrae of Indian origin, available in the Department of Anatomy, Dayanand Medical College and Hospital, Ludhiana were studied. Various dimensions were taken with vernier calipers, metric scale and graph paper. The dimensions were measured in millimetres and statistically analysed with paired t-test. Results: The mean of maximum anteroposterior diameter (max.APD) and maximum transverse diameter (max.TD) of Superior Articular Facet (SAF) was measured as 17.42mm±1.73 and 15.31mm±1.44 on the right side, 17.64mm±1.51 and 15.17mm±1.48 on left side. The mean Distance from Lateral most edge of SAF to Midline was measured as 22.56mm ± 2.37 and 22.40mm ± 2.16 on the right and left sides, respectively. The mean Distance from Tip of Transverse Process to Midline was 26.45mm ± 2.85 on the right and 26.03mm ± 2.64 on the left side. The mean Height of Dens was measured as 13.83mm ± 1.52, mean Width of Dens as 9.57mm ± 0.85. Width of Pedicle was measured as 10.52mm ± 1.99 and 10.61mm ± 1.67on right and left sides, respectively. Conclusion: The knowledge of these dimensions can provide useful information for safe planning of osseous fixation.

9.
Article | IMSEAR | ID: sea-183525

ABSTRACT

Background: The axis vertebra, exhibits complex and extensive variability in the morphology and there are vital neurovascular structures in its proximity. Knowledge of this variability is important for neurosurgeons, orthopaedicians, otorhynologists and other physicians who in everyday practice are in contact with disorders of the spine and their consequences. Objective: The aim was to evaluate various morphometric dimensions of axis vertebrae and to compare with the available data. Material and Methods: 50 dried human axis vertebrae of Indian origin, available in the Department of Anatomy, Dayanand Medical College and Hospital, Ludhiana were studied. Various dimensions were taken with vernier calipers, metric scale and graph paper. The dimensions were measured in millimetres and statistically analysed with paired t-test. Results: The mean of maximum anteroposterior diameter (max.APD) and maximum transverse diameter (max.TD) of Superior Articular Facet (SAF) was measured as 17.42mm±1.73 and 15.31mm±1.44 on the right side, 17.64mm±1.51 and 15.17mm±1.48 on left side. The mean Distance from Lateral most edge of SAF to Midline was measured as 22.56mm ± 2.37 and 22.40mm ± 2.16 on the right and left sides, respectively. The mean Distance from Tip of Transverse Process to Midline was 26.45mm ± 2.85 on the right and 26.03mm ± 2.64 on the left side. The mean Height of Dens was measured as 13.83mm ± 1.52, mean Width of Dens as 9.57mm ± 0.85. Width of Pedicle was measured as 10.52mm ± 1.99 and 10.61mm ± 1.67on right and left sides, respectively. Conclusion: The knowledge of these dimensions can provide useful information for safe planning of osseous fixation.

10.
Article | IMSEAR | ID: sea-183598

ABSTRACT

Background: Rh D is the most important Blood Group antigen after ABO Blood group antigen for transfusion purpose. All negative blood units by routine methods must be tested to detect weak D using IAT method. When the test for D and Du is positive, the label should read Rh(D) Positive . When the test for D and Du is negative, the label should read Rh(D) Negative. Objective: To know the prevalence of weak D in the donor population. No study has been done in this part of the country earlier. It will help in the knowledge of weak D, which is very important for better patient care and prevent allo-immunzation in blood recipients. Materials and Methods: Blood samples were tested by ID Gel technique or by tube method with two anti D reagents - anti-D IgM monoclonal and blend of anti-D IgM&IgG. All negative samples were further tested for weak D in IAT phase by LISS/Coombs' gel card. Results: A total of 13043 samples were tested from January 2011 to December 2013. 12196 were Rh positive and 847 were Rh D negative. Weak D was positive in 8 samples. Conclusion: The study shows the prevalence of weak D as 0.07% in blood donors who were primarily from in and around Jalandhar in Punjab. These donors may have posed problem to the recipients of blood and blood product and their detection prevented them from alloimunisation.

11.
Article | IMSEAR | ID: sea-183536

ABSTRACT

Background: Rh D is the most important Blood Group antigen after ABO Blood group antigen for transfusion purpose. All negative blood units by routine methods must be tested to detect weak D using IAT method. When the test for D and Du is positive, the label should read Rh(D) Positive . When the test for D and Du is negative, the label should read Rh(D) Negative. Objective: To know the prevalence of weak D in the donor population. No study has been done in this part of the country earlier. It will help in the knowledge of weak D, which is very important for better patient care and prevent allo-immunzation in blood recipients. Materials and Methods: Blood samples were tested by ID Gel technique or by tube method with two anti D reagents - anti-D IgM monoclonal and blend of anti-D IgM&IgG. All negative samples were further tested for weak D in IAT phase by LISS/Coombs' gel card. Results: A total of 13043 samples were tested from January 2011 to December 2013. 12196 were Rh positive and 847 were Rh D negative. Weak D was positive in 8 samples. Conclusion: The study shows the prevalence of weak D as 0.07% in blood donors who were primarily from in and around Jalandhar in Punjab. These donors may have posed problem to the recipients of blood and blood product and their detection prevented them from alloimunisation.

12.
Article in English | IMSEAR | ID: sea-178248

ABSTRACT

Background: Many people are affected by color blindness but most of them remain undetected as they simply adapt to the environment to certain extent and some remain unaware of the disease. Objective: To find out the prevalence rate of color blindness in students of ages 6 years to 15 years, in various schools of Jalandhar. Methods: A prospective study was done on 3259 students to identify the prevalence of color blindness. Students were examined with Ishihara Pseudoisochromatic Color Plates 38 edition. If the student was color blind, then it was further classified into its types. The data collected was complied and analyzed to evaluate the prevalence of color blindness, gender wise prevalence and prevalence of types of color blindness. Results: Students of 12 schools were screened in the age group of 6 to 15 years. 3259 students were included in the study; 1683(40.44%) were males and 1584 (59.55%) females. Color blindness was seen in 61 students (1.89%) including 55 (1.69%) males and 6(0.184%) females. Among the color blind 56(91.8 %) were protanopes, 5(8.2 %) were deuteranopes and none were tritanope. Among the protanopes, 52(92.8%) were males and 4 (7.2%) were females and in deuteranopes, percentage of males affected was 4(66.7 %) and females was 2(33.3%). Conclusion: Color blindness affects males more than females in this study similar to previous studies done. Protonopia is more common than deutronopia. Early school screening for color vision defect is recommended.

13.
Article in English | IMSEAR | ID: sea-182869

ABSTRACT

The aim of this article is to study the outcome of induction of labor using medical and surgical methods. Two hundred and twelve patients with >28 weeks pregnancy requiring induction of labor were studied for a period of 1 year in the Government Medical College and Rajindra Hospital, Patiala, Punjab. In 25 patients (Group 1), artificial rupture of membranes was done to induce labor, 52 patients were induced with oxytocin, and 83 patients were induced with misoprostol (Group 2). In 52 patients (Group 3), medical and surgical methods were used in combination. The incidence of labor induction came out to be 13.86%. The induction delivery interval was shortest in Group 3 (85.42% delivered within 12 h) compared to 62.72% and 64.60% in Groups 1 and 2, respectively. The lower segment cesarean section rate was least in Group 3 (7.69% vs 12% and 16.30%, respectively). Postpartum hemorrhage and maternal pyrexia were observed more in Group 1 (20% and 8%) than in Group 2 (2.96% and 0.74%) and Group 3 (5.77% and 3.85%). All methods were equally effective in induction of labor in terms of induction delivery interval and mode of delivery.

14.
Indian J Pathol Microbiol ; 2007 Jul; 50(3): 619-21
Article in English | IMSEAR | ID: sea-73238

ABSTRACT

This paper describes the clinical, radiological and cytomorphological findings of tumoral calcinosis in a twelve-year old boy with normal serum calcium levels and simultaneous involvement of the right shoulder and the left hip. The aim of presentation is to highlights the fact that clinicoradiological correlation and correct interpretation of cytologic findings can alleviate patients' anxiety and avoid unnecessary mutilating surgery in this uncommon but completely benign condition.


Subject(s)
Biopsy, Fine-Needle , Calcinosis/pathology , Child , Hip Joint/pathology , Humans , Joint Diseases/pathology , Male , Shoulder Joint/pathology , Tomography, X-Ray Computed
15.
Indian J Pathol Microbiol ; 2001 Jan; 44(1): 23-5
Article in English | IMSEAR | ID: sea-75127

ABSTRACT

500 blood donors were screened for G6PD deeiciency using micromethaemoglobin reduction (microMRT) test. Most of the blood donors were young adult males (95.8%). The overall incidence of G6PD deficiency was found to be 0.8%. There, was apparently decreased frequency of G6PD deficient blood donors with increasing age, and no relation could be ascertained between G6PD) deficiency and blood groups.


Subject(s)
Adult , Blood Donors , Female , Glucosephosphate Dehydrogenase/blood , Glucosephosphate Dehydrogenase Deficiency/blood , Humans , Male , Mass Screening , Oxidation-Reduction
16.
Indian J Physiol Pharmacol ; 2000 Jul; 44(3): 265-72
Article in English | IMSEAR | ID: sea-106874

ABSTRACT

Selenium is an essential micronutrient for animals. To determine whether its excess in diet induces morphological changes within the male reproductive system, a detailed qualitative and quantitative evaluation of the changes in the histology of the testis and cauda epididymis was undertaken in male rats. Adult male albino rats were fed 6 and 8 ppm Se in diet for 6 and 9 weeks. Each male consuming 6 ppm Se was mated with two untreated females, their offsprings were allowed to mature upto 12 weeks of age. The testes and cauda epididymes of male rats were prepared for light microscopy. Excess of dietary Se caused dose-time-dependent reduction in body weight and reproductive organ weights but increase in number of morphologically abnormal spermatozoa. Histopathological studies of the testes and cauda epididymis have revealed that Se-rich diets cause dose-time-dependent reduction in tubular diameter, epithelial height, number of spermatogenic cells and disintegration of cellular associations in the seminiferous tubules of testes along with reduction in the diameter of cauda epididymal tubules and pseudostratification of their epithelial lining. Progeny (feeding on normal diet) of paternally treated rats has shown retarded growth.


Subject(s)
Animals , Dose-Response Relationship, Drug , Epididymis/drug effects , Female , Glutathione Peroxidase/metabolism , Male , Rats , Selenium/administration & dosage , Spermatozoa/drug effects , Testis/drug effects
17.
Indian J Biochem Biophys ; 1999 Oct; 36(5): 325-9
Article in English | IMSEAR | ID: sea-28056

ABSTRACT

The dielectric properties of biologically and pharmaceutically important low-molecular weight ethylene glycols H(-OCH2CH2-)n -OH (n = 1,2,4,6) were investigated to clarify the effect of chain length on the dielectric properties. The measurement of dielectric constant and dielectric loss was carried out over the frequency range 200 MHz to 20 GHz at temperatures of 25 degrees C to 55 degrees C. It is found that in these molecules microwave dielectric losses are significant. The dispersion behaviour of these molecules can be represented by Cole-Cole equation. The dielectric properties of these homologous ethylene glycols are discussed in terms of the effects of chain length and intermolecular hydrogen bonds regarding the molecular conformations. These wide frequency range dielectric data have also been discussed in view of the suitable selection of the oligomer of ethylene glycol for cosmetic preparations and other pharmaceutical applications with the intention of protection of the skin from weak microwave radiations present in the surrounding environment. These systematic microwave dielectric data with frequency and temperature variation are not available and are provided in this paper.


Subject(s)
Ethylene Glycol/chemistry , Microwaves , Polymers
18.
Indian J Exp Biol ; 1999 May; 37(5): 509-11
Article in English | IMSEAR | ID: sea-61990

ABSTRACT

Treatment of rats with selenium (6 and 8 ppm in diet) for 6 and 9 weeks resulted in decrease in testicular protein, phospholipid content and LDH activity and an increase in the lipid, cholesterol content and activity of ACP and ALP. These alterations have been discussed in relation to interference of selenium in various metabolic processes of testis. It seems that selenium affects the oxido-reductase activity of glutathione and resulting in oxidative damage to testis.


Subject(s)
Animals , Cholesterol/metabolism , Diet , L-Lactate Dehydrogenase/metabolism , Male , Rats , Selenium/pharmacology , Testis/drug effects
19.
Indian J Med Sci ; 1998 Aug; 52(8): 341-7
Article in English | IMSEAR | ID: sea-67993

ABSTRACT

Self-care is an important component of diabetes control programme. A cross-sectional survey was carried out in a resettlement colony of Chandigarh and 60 diabetics aged 20 years and above were identified. Their knowledge and practices regarding diet, genital hygiene, care of foot, wound, complications of diabetes and medication was assessed using a semistructured interview schedule. Most of them (60%) opined that diabetic should consume whatever is cooked in the family. Forty eight diabetics knew that sweets and fatty foods should be avoided but only 18.3% were avoiding them. Genital hygiene was maintained by 51.7% and foot care was done by 63.3% through regular washing. Monitoring of blood sugar was poor (46.7%), only 3 knew and were continuing self testing of urine. Oral anti-diabetic drug compliance rate was 62.9%. None of the patients on insulin injections knew about self therapy. Knowledge regarding diabetic complications was partial. There is a need to reorient and motivate health personnels in educating diabetics about self-care.


Subject(s)
Adult , Aged , Cross-Sectional Studies , Diabetes Mellitus/diet therapy , Diet, Diabetic/statistics & numerical data , Diabetic Foot/prevention & control , Female , Glucose Tolerance Test/statistics & numerical data , Health Knowledge, Attitudes, Practice , Health Surveys , Humans , India , Male , Middle Aged , Patient Compliance/statistics & numerical data , Patient Education as Topic/statistics & numerical data , Self Care/statistics & numerical data
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